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Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.

The primary structures of interferon (IFN)-induced guanylate-binding proteins (GBPs) were deduced from cloned human and murine cDNAs. These proteins contained only two of the three sequence motifs typically found in GTP/GDP-binding proteins. The N(T)KXD motif, which is believed to confer guanine spe...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Cheng, Y S, Patterson, C E, Staeheli, P
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361367/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1715024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.9.4717-4725.1991
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