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Efficient neocentromere formation is suppressed by gene conversion to maintain centromere function at native physical chromosomal loci in Candida albicans

CENPA/Cse4 assembles centromeric chromatin on diverse DNA. CENPA chromatin is epigenetically propagated on unique and different centromere DNA sequences in a pathogenic yeast Candida albicans. Formation of neocentromeres on DNA, nonhomologous to native centromeres, indicates a role of non-DNA sequen...

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Autori principali: Thakur, Jitendra, Sanyal, Kaustuv
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613581/
https://ncbi.nlm.nih.gov/pubmed/23439889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.141614.112
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