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Overexpression of the multidrug resistance gene mdr3 in spontaneous and chemically induced mouse hepatocellular carcinomas.

Overexpression of a family of plasma membrane glycoproteins, known as P-glycoproteins, is commonly associated with multidrug resistance in animal cells. In rodents, three multidrug resistance (mdr or pgp) genes have been identified, but only two can confer the multidrug resistance phenotype upon tra...

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Pubblicato in:Mol Cell Biol
Autori principali: Teeter, L D, Becker, F F, Chisari, F V, Li, D J, Kuo, M T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361344/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2122232/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.11.5728-5735.1990
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