Pre-Diagnostic Leukocyte Genomic DNA Methylation and the Risk of Colorectal Cancer in Women

BACKGROUND: Abnormal one-carbon metabolism may lead to general genomic (global) hypomethylation, which may predispose an individual to the development of colorectal neoplasia. METHODS: We evaluated the association between pre-diagnostic leukocyte genomic DNA methylation level and the risk of colorec...

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Detalhes bibliográficos
Main Authors: Nan, Hongmei, Giovannucci, Edward L., Wu, Kana, Selhub, Jacob, Paul, Ligi, Rosner, Bernard, Fuchs, Charles S., Cho, Eunyoung
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613344/
https://ncbi.nlm.nih.gov/pubmed/23560049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059455
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