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Plexin B1 inhibits MET through direct association and regulates Shp2 expression in melanocytes

Plexin B1, the receptor for Semaphorin 4D (Sema4D), is expressed by melanocytes in the skin. We recently showed that Sema4D suppresses activation of the hepatocyte growth factor receptor, MET, in melanocytes, and that knockdown of Plexin B1 results in activation of MET. MET signaling mediates prolif...

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Dettagli Bibliografici
Autori principali: Soong, Joanne, Scott, Glynis
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613185/
https://ncbi.nlm.nih.gov/pubmed/23203808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.119487
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