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Plexin B1 inhibits MET through direct association and regulates Shp2 expression in melanocytes

Plexin B1, the receptor for Semaphorin 4D (Sema4D), is expressed by melanocytes in the skin. We recently showed that Sema4D suppresses activation of the hepatocyte growth factor receptor, MET, in melanocytes, and that knockdown of Plexin B1 results in activation of MET. MET signaling mediates prolif...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Soong, Joanne, Scott, Glynis
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613185/
https://ncbi.nlm.nih.gov/pubmed/23203808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.119487
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