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Role of chitosan co-formulation in enhancing interleukin-12 delivery and antitumor activity

Local delivery systems that provide sustained, high concentrations of antitumor cytokines in the tumor microenvironment while minimizing systemic dissemination are needed to realize the potential of cytokine-based immunotherapies. Recently, co-formulations of cytokines with chitosan solutions have b...

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Библиографические подробности
Главные авторы: Yang, Lirong, Zaharoff, David A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613143/
https://ncbi.nlm.nih.gov/pubmed/23453060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.02.031
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