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Estrogen increases latencies to seizures and levels of 5α-pregnan-3α-ol-20-one in hippocampus of wild-type, but not 5α-reductase knockout, mice
Sex steroids can influence seizures. Estrogen (E(2)), progesterone (P(4)), and its metabolite, 5α-pregnan-3α-ol-20-one (3α,5α-THP), in particular, have received much attention for exerting these effects. Typically, it is thought that E(2) precipitates seizures, and progestogens, such as P(4) and 3α,...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3613142/ https://ncbi.nlm.nih.gov/pubmed/19782646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yebeh.2009.08.016 |
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