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Making Muscle or Mitochondria by Selective Splicing of PGC-1α
Endurance training induces the transcriptional coactivator PGC-1α in skeletal muscle, promoting mitochondrial biogenesis and skeletal muscle remodeling. In a recent issue of Cell, Ruas et al. (2012) show that resistance training regulates the splicing of a novel isoform of PGC-1α (PGC-1α4), which is...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3613141/ https://ncbi.nlm.nih.gov/pubmed/23312277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.12.008 |
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