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Two isoforms of murine hck, generated by utilization of alternative translational initiation codons, exhibit different patterns of subcellular localization.

Mammalian hck, a member of the src family of tyrosine kinases, is expressed predominantly in cells of the myeloid and B-lymphoid lineages. Using mutational analysis, we have investigated the molecular basis of two immunoreactive forms of murine hck of 56 and 59 kDa found in numerous hemopoietic cell...

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Pubblicato in:Mol Cell Biol
Autori principali: Lock, P, Ralph, S, Stanley, E, Boulet, I, Ramsay, R, Dunn, A R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361298/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1875927/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.9.4363-4370.1991
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