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In situ distinction between steroid receptor binding and transactivation at a target gene.

We have developed a DNA interference assay in the yeast Saccharomyces cerevisiae that is designed to indicate the intracellular DNA-binding status of the estrogen receptor. The assay utilizes a promoter containing multiple copies of a GAL4-estrogen receptor binding sequence. This element is designed...

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Autors principals: McDonnell, D P, Nawaz, Z, O'Malley, B W
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC361296/
https://ncbi.nlm.nih.gov/pubmed/1875926
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