The Importance of IGHV Mutational Status in del(11q) and del(17p) Chronic Lymphocytic Leukemia

Limited outcome data exist for patients with chronic lymphocytic leukemia (CLL) with a poor-risk cytogenetic profile and a good-risk (mutated) immunoglobulin heavy-chain variable (IGHV) sequence. In a retrospective, single-institution review, 1 in 4 patients with del(11q or 17p) CLL had a mutated IG...

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Detalhes bibliográficos
Main Authors: Gladstone, Douglas E., Blackford, Amanda, Cho, Eunpi, Swinnen, Lode, Kasamon, Yvette, Gocke, Christopher D., Griffin, Constance A., Bolaños-Meade, Javier, Jones, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612932/
https://ncbi.nlm.nih.gov/pubmed/22285608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clml.2011.12.005
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