Derepression of mouse beta-major-globin gene transcription during erythroid differentiation.

Functional analysis of the mouse beta-major-globin gene promoter has revealed a negative regulatory element (-100 to -250 bp) which represses promoter activity in mouse erythroleukemia (MEL) cells. Promoter activity is induced 14-fold during terminal differentiation of MEL cells. Three major in vitr...

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Bibliographic Details
Main Authors: Macleod, K, Plumb, M
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC361293/
https://ncbi.nlm.nih.gov/pubmed/1875923
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