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Genotype and Tumor Locus Determine Expression Profile of Pseudohypoxic Pheochromocytomas and Paragangliomas

Pheochromocytomas (PHEOs) and paragangliomas (PGLs) related to mutations in the mitochondrial succinate dehydrogenase (SDH) subunits A, B, C, and D, SDH complex assembly factor 2, and the von Hippel-Lindau (VHL) genes share a pseudohypoxic expression profile. However, genotype-specific differences i...

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Detalhes bibliográficos
Main Authors: Shankavaram, Uma, Fliedner, Stephanie M J, Elkahloun, Abdel G, Barb, Jenifer J, Munson, Peter J, Huynh, Thanh T, Matro, Joey C, Turkova, Hana, Linehan, W Marston, Timmers, Henri J, Tischler, Arthur S, Powers, James F, de Krijger, Ronald, Baysal, Bora E, Takacova, Martina, Pastorekova, Silvia, Gius, David, Lehnert, Hendrik, Camphausen, Kevin, Pacak, Karel
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612915/
https://ncbi.nlm.nih.gov/pubmed/23555188
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