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Engineering the Protein N-Glycosylation Pathway in Insect Cells for Production of Biantennary, Complex N-Glycans

Insect cells, like other eucaryotic cells, modify many of their proteins by N-glycosylation. However, the endogenous insect cell N-glycan processing machinery generally does not produce complex, terminally sialylated N-glycans such as those found in mammalian systems. This difference in the N-glycan...

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Main Authors: Hollister, Jason, Grabenhorst, Eckart, Nimtz, Manfred, Conradt, Harald, Jarvis, Donald L.
Formato: Artigo
Idioma:Inglês
Publicado: 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612895/
https://ncbi.nlm.nih.gov/pubmed/12475259
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