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Mammalian target of rapamycin complex 1 activation negatively regulates Polo-like kinase 2-mediated homeostatic compensation following neonatal seizures

Homeostatic plasticity is characterized by compensatory changes in synaptic strength and intrinsic membrane properties in response to chronic changes in neuronal activity. Neonatal seizures are a naturally occurring source of neuronal overactivation and can lead to long-term epilepsy and cognitive d...

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Détails bibliographiques
Auteurs principaux: Sun, Hongyu, Kosaras, Bela, Klein, Peter M., Jensen, Frances E.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612683/
https://ncbi.nlm.nih.gov/pubmed/23479645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208010110
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