Učitavanje...
Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products
Ribosome stalling on eukaryotic mRNAs triggers cotranslational RNA and protein degradation through conserved mechanisms. For example, mRNAs lacking a stop codon are degraded by the exosome in association with its cofactor, the SKI complex, whereas the corresponding aberrant nascent polypeptides are...
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| Glavni autori: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3612664/ https://ncbi.nlm.nih.gov/pubmed/23479637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221724110 |
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