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Aging does not alter the number or phenotype of putative stem/progenitor cells in the neurogenic region of the hippocampus

To investigate whether dramatically waned dentate neurogenesis during aging is linked to diminution in neural stem/progenitor cell (NSC) number, we counted cells immunopositive for Sox-2 (a putative marker of NSCs) in the subgranular zone (SGZ) of young, middle-aged and aged F344 rats. The young SGZ...

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Autores principales: Hattiangady, Bharathi, Shetty, Ashok K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612500/
https://ncbi.nlm.nih.gov/pubmed/17092610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2006.09.015
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