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Striking similarities between the regulatory mechanisms governing yeast mating-type genes and mammalian major histocompatibility complex genes.

Expression of a mammalian major histocompatibility complex (MHC) class I gene is in part regulated by a silencer DNA sequence element which binds a complex of silencer factors. This negative regulatory system is shown to be strikingly similar to the yeast alpha 2 mating-type repression system. A mod...

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Foilsithe in:Mol Cell Biol
Main Authors: Weissman, J D, Singer, D S
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 1991
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361249/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2072916/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.8.4228
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