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Neutron-encoded mass signatures for multi-plexed proteome quantification
We describe a protein quantification method that exploits the subtle mass differences caused by neutron-binding energy variation in stable isotopes. These mass differences are synthetically encoded into amino acids and incorporated into yeast and mouse proteins with metabolic labeling; analysis with...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3612390/ https://ncbi.nlm.nih.gov/pubmed/23435260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2378 |
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