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Functional characterization of the human hypoxanthine phosphoribosyltransferase gene promoter: evidence for a negative regulatory element.

The enzyme hypoxanthine phosphoribosyltransferase (HPRT) catalyzes the metabolic salvage of the purine bases hypoxanthine and guanine. We previously characterized the genomic structure of the human HPRT gene and described its promoter sequence. In this report, we identify cis-acting transcriptional...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Rincón-Limas, D E, Krueger, D A, Patel, P I
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361235/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1712904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.8.4157
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