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HDAC1 Inhibition by Maspin Abrogates Epigenetic Silencing of Glutathione S-Transferase Pi (GSTp) in Prostate Carcinoma Cells
Both maspin and glutathione s-transferase pi (GSTp) are implicated as tumor suppressors and down regulated in human prostate cancer. It is well established that GSTp down-regulation is through DNA methylation-based silencing. We report here that maspin expression in prostate cancer cell line DU145 r...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3612175/ https://ncbi.nlm.nih.gov/pubmed/21622623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0505 |
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