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Conditional Tat protein expression in the GT-tg bigenic mouse brain induces gray matter density reductions

Tat (Trans-activator of transcription) is implicated in the neuropathogenesis of HIV-1 infection and known to contribute to neuronal damage and learning and memory impairments. However, direct neuroanatomical demonstration of Tat pathobiology is limited. GT-tg bigenic mice with a doxycycline (Dox)-i...

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Detalhes bibliográficos
Main Authors: Carey, Amanda N., Liu, Xiaoxu, Mintzopoulos, Dionyssios, Paris, Jason J., Muschamp, John W., McLaughlin, Jay P., Kaufman, Marc J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612135/
https://ncbi.nlm.nih.gov/pubmed/23269344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2012.12.018
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