Diesel Exhaust Particles Induce Cysteine Oxidation and S-Glutathionylation in House Dust Mite Induced Murine Asthma

BACKGROUND: Diesel exhaust particle (DEP) exposure enhances allergic inflammation and has been linked to the incidence of asthma. Oxidative stress on the thiol molecules cysteine (Cys) and glutathione (GSH) can promote inflammatory host responses. The effect of DEP on the thiol oxidation/reduction (...

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Main Authors: Lee, Gerald B., Brandt, Eric B., Xiao, Chang, Gibson, Aaron M., Le Cras, Timothy D., Brown, Lou Ann S., Fitzpatrick, Anne M., Khurana Hershey, Gurjit K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612047/
https://ncbi.nlm.nih.gov/pubmed/23555996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060632
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