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Pharmacogenomics in pediatric leukemia

PURPOSE OF REVIEW: The therapeutic index of many medications, especially in children, is very narrow with substantial risk for toxicity at doses required for therapeutic effects. This is particularly relevant to cancer chemotherapy, where the risk of toxicity must be balanced against potential subop...

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Detalhes bibliográficos
Main Authors: Paugh, Steven W., Stocco, Gabriele, Evans, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612020/
https://ncbi.nlm.nih.gov/pubmed/20861736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOP.0b013e32833fde85
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