Maturation and function of cystic fibrosis transmembrane conductance regulator variants bearing mutations in putative nucleotide-binding domains 1 and 2.

One feature of the mutations thus far found to be associated with the disease cystic fibrosis (CF) is that many of them are clustered within the first nucleotide-binding domain (NBD) of the CF transmembrane conductance regulator (CFTR). We sought to discover the molecular basis for this clustering b...

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Autores principales: Gregory, R J, Rich, D P, Cheng, S H, Souza, D W, Paul, S, Manavalan, P, Anderson, M P, Welsh, M J, Smith, A E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC361177/
https://ncbi.nlm.nih.gov/pubmed/1712898
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