Mapping of replication initiation sites in mammalian genomes by two-dimensional gel analysis: stabilization and enrichment of replication intermediates by isolation on the nuclear matrix.

Two complementary two-dimensional gel electrophoretic techniques have recently been developed that allow initiation sites to be mapped with relative precision in eukaryotic genomes at least as complex as those of yeast and Drosophila melanogaster. We reported the first application of these mapping m...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Dijkwel, P A, Vaughn, J P, Hamlin, J L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361168/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2072896/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.8.3850-3859.1991
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