Tissue-specific regulatory T cells: biomarker for acute graft-vs-host disease and survival

Regulatory T cells (Tregs) are a subset of CD4(+) T cells that are characterized by the expression of CD25 and Foxp3 and are capable of suppressing alloimmune responses. We assessed whether high frequencies of circulating skin or gut tissue–specific Tregs at engraftment could predict acute graft-vs-...

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Main Authors: Engelhardt, Brian G., Sengsayadeth, Salyka M., Jagasia, Madan, Savani, Bipin N., Kassim, Adetola A., Lu, Pengcheng, Shyr, Yu, Yoder, Sandra M., Rock, Michael T., Crowe, James E.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611587/
https://ncbi.nlm.nih.gov/pubmed/22885125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2012.08.002
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