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Efficacy of the oral neurokinin-1 receptor antagonist aprepitant administered with ondansetron for the prevention of postoperative nausea and vomiting

BACKGROUND: 5-HT(3) receptor antagonist, dexamethasone and droperidol were used for the prevention of postoperative nausea and vomiting (PONV). Recently, neurokinin-1 (NK1) antagonist has been used for PONV. We evaluated the effect of oral aprepitant premedication in addition to ondansetron. METHODS...

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Autors principals: Lim, Chae Seong, Ko, Young-Kwon, Kim, Yoon-Hee, Park, Sang-Il, Kim, Jae-Kook, Kim, Myoung-Joong, Kim, Hyun-Joong
Format: Artigo
Idioma:Inglês
Publicat: The Korean Society of Anesthesiologists 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611069/
https://ncbi.nlm.nih.gov/pubmed/23560185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4097/kjae.2013.64.3.212
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