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An initiation zone of chromosomal DNA replication located upstream of the c-myc gene in proliferating HeLa cells.

Studies on origins of DNA replication in mammalian cells have long been hampered by a lack of methods sensitive enough for the localization of such origins in chromosomal DNA. We have employed a new method for mapping origins, based on polymerase chain reaction amplification of nascent strand segmen...

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Publicat a:Mol Cell Biol
Autors principals: Vassilev, L, Johnson, E M
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361105/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2201906/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.9.4899-4904.1990
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