Yüklüyor......

Inhibition of Neuronal Degenerin/Epithelial Na(+) Channels by the Multiple Sclerosis Drug 4-Aminopyridine

The voltage-gated K(+) (Kv) channel blocker 4-aminopyridine (4-AP) is used to target symptoms of the neuroinflammatory disease multiple sclerosis (MS). By blocking Kv channels, 4-AP facilitates action potential conduction and neurotransmitter release in presynaptic neurons, lessening the effects of...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Boiko, Nina, Kucher, Volodymyr, Eaton, Benjamin A., Stockand, James D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611011/
https://ncbi.nlm.nih.gov/pubmed/23404498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.449413
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!