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Dimerization of Bacterial Diaminopimelate Epimerase Is Essential for Catalysis
Diaminopimelate (DAP) epimerase is involved in the biosynthesis of meso-DAP and lysine, which are important precursors for the synthesis of peptidoglycan, housekeeping proteins, and virulence factors in bacteria. Accordingly, DAP epimerase is a promising antimicrobial target. Previous studies report...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610995/ https://ncbi.nlm.nih.gov/pubmed/23426375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.450148 |
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