Interaction with Cyclin H/Cyclin-dependent Kinase 7 (CCNH/CDK7) Stabilizes C-terminal Binding Protein 2 (CtBP2) and Promotes Cancer Cell Migration

CtBP2 has been demonstrated to possess tumor-promoting capacities by virtue of up-regulating epithelial-mesenchymal transition (EMT) and down-regulating apoptosis in cancer cells. As a result, cellular CtBP2 levels are considered a key factor determining the outcome of oncogenic transformation. How...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Yuchan, Liu, Fang, Mao, Feng, Hang, Qinlei, Huang, Xiaodong, He, Song, Wang, Yingying, Cheng, Chun, Wang, Huijie, Xu, Guangfei, Zhang, Tianyi, Shen, Aiguo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2013
Pynciau:
Cell Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610975/
https://ncbi.nlm.nih.gov/pubmed/23393140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.432005
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