Negative regulation of globin gene expression during megakaryocytic differentiation of a human erythroleukemic cell line.
The human erythroleukemic cell line K562 was used as a model for analysis of the mechanisms responsible for alterations in gene expression during differentiation. K562 cells normally synthesize fetal hemoglobin (gamma-globin), but treatment with tumor-promoting phorbol esters (phorbol myristate acet...
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| Udgivet i: | Mol Cell Biol |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1991
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361092/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2046667/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.7.3528-3536.1991 |
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