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Differential Evolutionary Fate of an Ancestral Primate Endogenous Retrovirus Envelope Gene, the EnvV Syncytin, Captured for a Function in Placentation

Syncytins are envelope genes of retroviral origin that have been co-opted for a role in placentation. They promote cell–cell fusion and are involved in the formation of a syncytium layer—the syncytiotrophoblast—at the materno-fetal interface. They were captured independently in eutherian mammals, an...

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Autori principali: Esnault, Cécile, Cornelis, Guillaume, Heidmann, Odile, Heidmann, Thierry
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610889/
https://ncbi.nlm.nih.gov/pubmed/23555306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003400
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