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Reduced RhoA activity mediates acute alcohol intoxication-induced inhibition of lymphatic myogenic constriction despite increased cytosolic [Ca(2+)]

OBJECTIVES: We previously showed that acute alcohol intoxication (AAI) reduces lymphatic myogenic constriction in response to step increases in luminal pressure. Because of the known role of Ca(2+) in smooth muscle contractile responses, we investigated how alcohol impacts cyclic Ca(2+) and whether...

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Detalhes bibliográficos
Main Authors: Souza-Smith, Flavia M., Molina, Patricia E., Breslin, Jerome W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610832/
https://ncbi.nlm.nih.gov/pubmed/23237297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12032
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