Excess wild-type p53 blocks initiation and maintenance of simian virus 40 transformation.

Wild-type (wt) murine p53 has been tested for its ability to block and reverse the transforming effects of simian virus 40 (SV40) large T antigen. Established and precrisis mouse cells overexpressing exogenously introduced wt p53 became resistant to SV40 transformation. The introduction of excess wt...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Fukasawa, K, Sakoulas, G, Pollack, R E, Chen, S
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361080/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1646391/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.7.3472-3483.1991
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