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Reactive Intermediates Produced from Metabolism of the Vanilloid Ring of Capsaicinoids by P450 Enzymes

This study characterized electrophilic and radical products derived from metabolism of capsaicin by cytochrome P450 and peroxidase enzymes. Multiple glutathione and β-mercaptoethanol conjugates (a.k.a., adducts), derived from trapping of quinone methide and quinone intermediates of capsaicin, its an...

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Detalhes bibliográficos
Main Authors: Reilly, Christopher A., Henion, Fred, Bugni, Tim S., Ethirajan, Manivannan, Stockmann, Chris, Pramanik, Kartick C., Srivastava, Sanjay K., Yost, Garold S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610763/
https://ncbi.nlm.nih.gov/pubmed/23088752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300366k
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