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Cartilage–Specific Over-Expression of CCN Family Member 2/Connective Tissue Growth Factor (CCN2/CTGF) Stimulates Insulin-Like Growth Factor Expression and Bone Growth

Previously we showed that CCN family member 2/connective tissue growth factor (CCN2) promotes the proliferation, differentiation, and maturation of growth cartilage cells in vitro. To elucidate the specific role and molecular mechanism of CCN2 in cartilage development in vivo, in the present study w...

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Detalhes bibliográficos
Main Authors: Tomita, Nao, Hattori, Takako, Itoh, Shinsuke, Aoyama, Eriko, Yao, Mayumi, Yamashiro, Takashi, Takigawa, Masaharu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610707/
https://ncbi.nlm.nih.gov/pubmed/23555635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059226
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