Cartilage–Specific Over-Expression of CCN Family Member 2/Connective Tissue Growth Factor (CCN2/CTGF) Stimulates Insulin-Like Growth Factor Expression and Bone Growth

Previously we showed that CCN family member 2/connective tissue growth factor (CCN2) promotes the proliferation, differentiation, and maturation of growth cartilage cells in vitro. To elucidate the specific role and molecular mechanism of CCN2 in cartilage development in vivo, in the present study w...

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Autores principales: Tomita, Nao, Hattori, Takako, Itoh, Shinsuke, Aoyama, Eriko, Yao, Mayumi, Yamashiro, Takashi, Takigawa, Masaharu
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610707/
https://ncbi.nlm.nih.gov/pubmed/23555635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059226
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