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Cartilage–Specific Over-Expression of CCN Family Member 2/Connective Tissue Growth Factor (CCN2/CTGF) Stimulates Insulin-Like Growth Factor Expression and Bone Growth

Previously we showed that CCN family member 2/connective tissue growth factor (CCN2) promotes the proliferation, differentiation, and maturation of growth cartilage cells in vitro. To elucidate the specific role and molecular mechanism of CCN2 in cartilage development in vivo, in the present study w...

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Bibliografiske detaljer
Main Authors: Tomita, Nao, Hattori, Takako, Itoh, Shinsuke, Aoyama, Eriko, Yao, Mayumi, Yamashiro, Takashi, Takigawa, Masaharu
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610707/
https://ncbi.nlm.nih.gov/pubmed/23555635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059226
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