Cartilage–Specific Over-Expression of CCN Family Member 2/Connective Tissue Growth Factor (CCN2/CTGF) Stimulates Insulin-Like Growth Factor Expression and Bone Growth

Previously we showed that CCN family member 2/connective tissue growth factor (CCN2) promotes the proliferation, differentiation, and maturation of growth cartilage cells in vitro. To elucidate the specific role and molecular mechanism of CCN2 in cartilage development in vivo, in the present study w...

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Autors principals: Tomita, Nao, Hattori, Takako, Itoh, Shinsuke, Aoyama, Eriko, Yao, Mayumi, Yamashiro, Takashi, Takigawa, Masaharu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610707/
https://ncbi.nlm.nih.gov/pubmed/23555635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059226
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