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Nephrogenic Diabetes Insipidus: Essential Insights into the Molecular Background and Potential Therapies for Treatment

The water channel aquaporin-2 (AQP2), expressed in the kidney collecting ducts, plays a pivotal role in maintaining body water balance. The channel is regulated by the peptide hormone arginine vasopressin (AVP), which exerts its effects through the type 2 vasopressin receptor (AVPR2). Disrupted func...

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Detalhes bibliográficos
Main Authors: Moeller, Hanne B., Rittig, Søren, Fenton, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610677/
https://ncbi.nlm.nih.gov/pubmed/23360744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2012-1044
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