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CRL2(LRR-1) E3-Ligase Regulates Proliferation and Progression through Meiosis in the Caenorhabditis elegans Germline
The ubiquitin-proteolytic system controls the stability of proteins in space and time. In this study, using a temperature-sensitive mutant allele of the cul-2 gene, we show that CRL2(LRR-1) (CUL-2 RING E3 ubiquitin-ligase and the Leucine Rich Repeat 1 substrate recognition subunit) acts at multiple...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610609/ https://ncbi.nlm.nih.gov/pubmed/23555289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003375 |
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