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Effect of Alzheimer Disease Risk Genes on Trajectories of Cognitive Function in the Cardiovascular Health Study

OBJECTIVE: Patients with late onset Alzheimer disease (AD) vary widely in their trajectory of cognitive decline. Genetic variations in CLU, PICALM, and CR1 are associated with AD, but it is unknown if they exert their effects via altering cognitive trajectory in elderly subjects at risk for AD. METH...

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Detalhes bibliográficos
Main Authors: Sweet, Robert A., Seltman, Howard, Emanuel, James E., Lopez, Oscar L., Becker, James T., Bis, Joshua C., Weamer, Elise A., DeMichele-Sweet, Mary Ann A., Kuller, Lewis H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610571/
https://ncbi.nlm.nih.gov/pubmed/22952074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2012.11121815
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