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The Effects of Select Histidine to Cysteine Mutations on Transcriptional Regulation by E. coli RcnR()
The RcnR metalloregulator represses the transcription of the Co(II) and Ni(II) exporter, RcnAB. Previous studies have shown that Co(II) and Ni(II) bind to RcnR in six-coordinate sites, resulting in de-repression. Here, the roles of His60, His64, and His67 in specific metal recognition are examined....
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610428/ https://ncbi.nlm.nih.gov/pubmed/23215580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300886q |
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