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Glucose-induced hyperaccumulation of cyclic AMP and defective glucose repression in yeast strains with reduced activity of cyclic AMP-dependent protein kinase.

Addition of glucose or related fermentable sugars to derepressed cells of the yeast Saccharomyces cerevisiae triggers a RAS-mediated cyclic AMP (cAMP) signal that induces a protein phosphorylation cascade. In yeast mutants (tpk1w1, tpk2w1, and tpk3w1) containing reduced activity of cAMP-dependent pr...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Mbonyi, K, van Aelst, L, Argüelles, J C, Jans, A W, Thevelein, J M
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1990
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361038/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2201893/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.9.4518-4523.1990
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