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Measuring Dynamic Changes in Histone Modifications and Nucleosome Density during Activated Transcription in Budding Yeast

Chromatin immunoprecipitation is widely utilized to determine the in vivo binding of factors that regulate transcription. This procedure entails formaldehyde-mediated cross-linking of proteins and isolation of soluble chromatin followed by shearing. The fragmented chromatin is subjected to immunopre...

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Detalhes bibliográficos
Main Authors: Govind, Chhabi K., Ginsburg, Daniel, Hinnebusch, Alan G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610330/
https://ncbi.nlm.nih.gov/pubmed/22183585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-477-3_2
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