Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

BACKGROUND: Macrophages play a dual role in multiple sclerosis (MS) pathology. They can exert neuroprotective and growth promoting effects but also contribute to tissue damage by production of inflammatory mediators. The effector function of macrophages is determined by the way they are activated. S...

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Main Authors: Vogel, Daphne YS, Vereyken, Elly JF, Glim, Judith E, Heijnen, Priscilla DAM, Moeton, Martina, van der Valk, Paul, Amor, Sandra, Teunissen, Charlotte E, van Horssen, Jack, Dijkstra, Christine D
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610294/
https://ncbi.nlm.nih.gov/pubmed/23452918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-35
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