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An investigation of the effects of the antioxidants, ebselen or N-acetyl cysteine on human peripheral blood mononuclear cells and T cells

BACKGROUND: The research literature has documented age-related increases in genetic damage, including oxidative DNA damage, in human T lymphocytes, in vitro and ex vivo. Such damage has the potential to interfere with the ability of the T cells to proliferate at times when they need to, such as when...

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Bibliographic Details
Main Authors: Marthandan, Shiva, Hyland, Paul, Pawelec, Graham, Barnett, Yvonne
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610132/
https://ncbi.nlm.nih.gov/pubmed/23432994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4933-10-7
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