Guanylate-binding protein 1 expression from embryonal endothelial progenitor cells reduces blood vessel density and cellular apoptosis in an axially vascularised tissue-engineered construct

BACKGROUND: Guanylate binding protein-1 (GBP-1) is a large GTPase which is actively secreted by endothelial cells. It is a marker and intracellular inhibitor of endothelial cell proliferation, migration, and invasion. We previously demonstrated that stable expression of GBP-1 in murine endothelial p...

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Autores principales: Bleiziffer, Oliver, Hammon, Matthias, Arkudas, Andreas, Taeger, Christian D, Beier, Justus P, Amann, Kerstin, Naschberger, Elisabeth, Stürzl, Michael, Horch, Raymund E, Kneser, Ulrich
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610105/
https://ncbi.nlm.nih.gov/pubmed/23217187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-12-94
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