Long-term strain improvements accumulate mutations in regulatory elements responsible for hyper-production of cellulolytic enzymes

Long-term strain improvements through repeated mutagenesis and screening have generated a hyper-producer of cellulases and hemicellulases from Penicillium decumbens 114 which was isolated 30 years ago. Here, the genome of the hyper-producer P. decumbens JU-A10-T was sequenced and compared with that...

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Bibliografiske detaljer
Main Authors: Liu, Guodong, Zhang, Lei, Qin, Yuqi, Zou, Gen, Li, Zhonghai, Yan, Xing, Wei, Xiaomin, Chen, Mei, Chen, Ling, Zheng, Kai, Zhang, Jun, Ma, Liang, Li, Jie, Liu, Rui, Xu, Hai, Bao, Xiaoming, Fang, Xu, Wang, Lushan, Zhong, Yaohua, Liu, Weifeng, Zheng, Huajun, Wang, Shengyue, Wang, Chengshu, Xun, Luying, Zhao, Guo-Ping, Wang, Tianhong, Zhou, Zhihua, Qu, Yinbo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610096/
https://ncbi.nlm.nih.gov/pubmed/23535838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01569
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