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Expression of a foreign gene in a line of transgenic mice is modulated by a chromosomal position effect.

Unusual aberrant expression of a foreign gene in a particular transgenic mouse line is often attributed to chromosomal position effect, although proof of this is lacking. An alternative explanation is that expression has been modified by the arrangement of multiple copies of the foreign gene at the...

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Publicat a:Mol Cell Biol
Autors principals: al-Shawi, R, Kinnaird, J, Burke, J, Bishop, J O
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360995/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2304463/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.3.1192
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