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GENETIC BASIS FOR THE INCREASED EXPRESSION OF VACUOLAR H+ TRANSLOCATING ATPASE GENES UPON IMATINIB TREATMENT IN HUMAN LYMPHOBLASTOID CELLS
PURPOSE: The role of v-ATPases in cancer biology is being increasingly recognized. Yeast studies indicate that the tyrosine-kinase inhibitor imatinib may interact with the v-ATPase genes and alter the course of cancer progression. Data from humans in this regard is lacking. METHODS: We constructed 5...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3609897/ https://ncbi.nlm.nih.gov/pubmed/23420437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-013-2110-4 |
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