GENETIC BASIS FOR THE INCREASED EXPRESSION OF VACUOLAR H+ TRANSLOCATING ATPASE GENES UPON IMATINIB TREATMENT IN HUMAN LYMPHOBLASTOID CELLS

PURPOSE: The role of v-ATPases in cancer biology is being increasingly recognized. Yeast studies indicate that the tyrosine-kinase inhibitor imatinib may interact with the v-ATPase genes and alter the course of cancer progression. Data from humans in this regard is lacking. METHODS: We constructed 5...

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Main Authors: Kulkarni, Hemant, Göring, Harald H.H., Curran, Joanne E, Diego, Vincent, Dyer, Thomas D., Cole, Shelley, Walder, Ken R, Collier, Greg R., Blangero, John, Carless, Melanie A
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609897/
https://ncbi.nlm.nih.gov/pubmed/23420437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-013-2110-4
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